Another RELAPSE - Starting Ninlaro soon

Another relapse.

After months of watching Doug's myeloma blood panel results climbing, the oncologist is certain he is relapsing again. So he is adding a new drug to what Doug is already taking. Ixazomib (brand name Ninlaro) is a capsule - the first oral proteasome inhibitor. The good thing is that Doug won't be needing infusions yet.
There are a few possible side effects to watch for:
1. Low blood counts
2. More G.I. upsets
3. Nausea
4. Diarrhea
5. Nerve damage

He will be monitored closely for the nerve damage. Doug already has peripheral nerve damage in his feet from a related drug, Velcade. If he starts to feel any tingling, pins and needles, pain or numbness, the doc said to immediately report it. This drug will be stopped if the symptoms are severe. Nerve damage is not reversible.

It will take a couple of weeks before he can start the ixazomib - gotta get insurance approval first. It is an approved drug, so approval shouldn't be a problem, just takes time.

So Doug's drug regime will be: Pomalyst, cytoxan, prednisone, ixazomib. All pills.

Periods of remission, followed by relapses, are standard for Multiple Myeloma.

Doug has had some good remissions. In fact, he feels pretty good right now. If it wasn't for the blood tests, we wouldn't know he is relapsing.
He has been doing a lot of yard work this summer. We have planted yarrow, an aspen tree, and silver lace vines. He has dug all the holes - which in this area means dealing with lots of rocks! Some of the rocks he has dug up are melon size.

In August, it will be 10 years since diagnosis. Amazing. We've dealt with some hard things but we have so very many things we are thankful for.

We have friends who have life threatening medical conditions - with no treatment available. We are very thankful there is treatment, even though as yet no cure, for myeloma.

Love to all.