Friday, September 13, 2013

Light Chain Deposition Disease?

We went to the nephrologist today for an initial consultation; we were sent by our myeloma specialist. We like Dr. F, the nephrologist. She used to practice in Denver but moved to Fairplay which is a small mountain town. She seems to be a real outdoorsy person, explains things well and she has a good sense of humor.

She did a physical exam, complete history. She found some leg edema. Doug gave a urine sample; it showed a lot of protein, and "casts". The urine sample will be sent to an outside lab for more testing.
The most recent lab work shows the creatinine has come down, from a high of 2 to 1.1 - that is good.

With Doug's history of multiple myeloma, and protein and casts in urine, Dr. Fitting feels he may have "light chain deposition disease". That sometimes occurs in myeloma patients but is not common.  Click here for information on LCDD

As I understand it, with LCCD, the myeloma proteins "clog" the kidney tubules and affect the kidney's ability to filter the urine. Treatment would be to get the myeloma back under control. No one has clearly stated it yet, but it seems Doug's myeloma has relapsed again.

Dr. F did say that a kidney biopsy might not be needed, since Doug has a known diagnosis of MM.

When we see the myeloma specialist on September 19th, he will give us the result of the bone marrow biopsy, and hopefully he will have a plan.

All this is a big concern, but we trust in God.

Love to all.

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