Kappa/Lambda Ratio Low; Early Relapse?

We got the results of the latest myeloma panel. Up to now, both the Lambda and Kappa light chains have been rising - but the ratio has been within normal limits. Now the Lambda is rising and Kappa is dropping, so the ratio is low. The specialist has been watching, and he said as long as both go up, it could mean recovery of immune system. If Lambda goes up more than Kappa, it could mean a relapse.

And now the myeloma panel shows a slight M-spike. This is the first time we've seen an M-spike since the myeloma mutated to light chain deposition disease back in 2011. Interesting, but may not be anything to be concerned about.

We have faith in the specialist and we know he has a plan, so we are not worried, just alert for changes.  Knowing there are new drugs available is reassuring.
We also have faith and trust in God, and we know HE has a plan!

Both Doug and I have been expecting another relapse at some point, that's the nature of the beast. Sometimes the myeloma sleeps, but it always awakens eventually.
Meanwhile, Doug feels good and we are grateful.

Love to all.

"Peace isn’t the absence of the dark. Peace is the assurance of God’s presence in the midst of the dark." Ann Voskamp 

IgG now, was IgA

The regular monthly trip to Denver today. We had an 8:30 a.m. appointment so left at 5:30. It was already almost light out, thankfully.
Lab results are mostly okay, with just a few borderline but nothing alarming. We won't get the myeloma panel results for 5 to 7 days.
Interestingly, Doug's myeloma has changed from IgA Lambda to IgG. The specialist isn't sure what this means, either a lab error or the myeloma is changing. But he doesn't think it has any significance as to treatment in the future.
Doug is still on chemo vacation. He's not having clinical problems (aside from the neuropathy) so the specialist doesn't want to initiate any new drugs yet.

Doug didn't get the Zometa infusion this time, since it had been only three weeks since the last one. He'll get it next month. That saved an hour of infusion time.

So it was a good visit. Afterward we stopped for a late breakfast - in the hospital cafeteria of all places. They have really good hash browns and sausage. Eggs are passable. And we didn't have to move the car.

We are counting our blessings and praising the Lord!

Love to all.